The story begins with Andre Bishop's promising boxing career, as he strives to achieve greatness in the sport. However, his journey takes a dramatic turn when he is wrongfully accused of a crime and is sent to prison. While incarcerated, Bishop must navigate the brutal and unforgiving world of prison boxing to survive.
As the plot unfolds, players witness Bishop's resilience and determination as he fights his way through the prison ranks. Along the way, he forms alliances and confronts formidable opponents, both inside and outside the ring.